Welcome to the Pfleger Lab‽
We are multi-disciplined team of researchers focused on using metabolic engineering techniques to produce value-added fuels and chemicals. With backgrounds ranging from chemical engineering to molecular biology, we are well equipped to create a variety of solutions to any research problem. We are currently working on a variety of projects in different organisms, including Escherichia coli and Synechococcus sp. 7002. Led by Professor Brian Pfleger, we hope to solve relevant societal problems using our expertise in biology.
Qiang Yan a 2018 PhD graduate of Virginia Commonwealth University (Prof Stephen Fong) joined the group. Welcome Wilson.
Congratulations Chris Mehrer on winning a poster prize for his work on engineering E. coli to produce medium chain fatty alcohols. The work was recently published in Metabolic Engineering.
Congratulations to Brian Pfleger for receiving this prestigious award from the American Chemical Society Biochemical Technology Division.
- More News posts
- Korosh TC, Markley AL, Clark RL, McGinley LL, McMahon KD, Pfleger BF. Engineering Photosynthetic Production of L-lysine. Metabolic Engineering (2017) Nov;44:273-283 DOI: 1016/j.ymben.2017.10.010
- Rand JM, Pisithkul T, Clark RL, Thiede JM, Mehrer CR, Agnew DA, Campbell CE, Markley AL, Price MN, Ray J, Wetmore KM, Suh Y, Arkin AP, Deutschbauer AM, Amador Noguez D, Pfleger BF. A metabolic pathway for catabolizing levulinic acid in bacteria. Nature Microbiology. Dec;2(12):1624-1634. (2017) DOI: doi:10.1038/s41564-017-0028-z
- Grisewood MJ, Hernandez Lozada NJ, Thoden J, Gifford N, Mendez-Perez D, Schoenberger HA, Allan MF, Floy M, Lai RY, Holden HM, Pfleger BF, Maranas CD. Computational redesign of acyl-ACP thioesterase with improved selectivity towards medium-chain fatty acids. ACS Catalysis. 7, 3837–3849 (2017) DOI: 1021/acscatal.7b00408
- Copeland MF, Politz MP, Johnson CB, Markley AL, Pfleger BF. A transcription activator-like effector induction system mediated by proteolytic degradation. Nature Chemical Biology. Apr;12(4):254-60 (2016). DOI: 10.1038/nchembio.2021